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Forthcoming Publication of Ethnopharmacologic Search for Psychoactive Drugs [ESPD55]

Forthcoming Publication of Ethnopharmacologic Search for Psychoactive Drugs [ESPD55]

Exploring ESPD55: The Next Chapter in the Ethnopharmacologic Search for Psychoactive Drugs

In 2022, the McKenna Academy of Natural Philosophy hosted the third conference of the Ethnopharmacologic Search for Psychoactive Drugs (ESPD) symposium—ESPD55, marking 55 years since the original landmark conference in 1967 held in San Francisco sponsored by the U.S. Department for Mental Health. The third conference brought together some of the most respected voices in ethnobotany, pharmacology, anthropology, and Indigenous medicine to explore the evolving science and cultural relevance of psychoactive plant medicines.

An essential reference on the research and social impacts shaping the future of psychedelic science.

Synergetic Press is proud to publish the proceedings of the 2022 conference where over thirty papers were presented covering a wide spectrum of topics, including ancient and contemporary uses of psychoactive substances, the intersection of traditional knowledge and modern science, pharmacology, conservation, law and policy, and the cultural and spiritual significance of these compounds.

The conference program was organized into thematic “spheres”—Ethnosphere, Phytosphere, Mycosphere, and Sonosphere—highlighting the diverse ways psychoactive plants, fungi, and even sound have shaped human societies and consciousness. Presentations ranged from archaeological evidence of ancient plant use and indigenous perspectives on coca and ayahuasca, to modern neuroscience, sound as a psychoactive medium, and the evolving legal landscape for psychedelics.

ESPD55 also fostered collaboration between established experts and emerging voices, emphasizing the importance of biocultural conservation, respect for indigenous wisdom, and responsible innovation in psychedelic science. 

With contributions from luminaries like Dennis McKenna, Paul Stamets, David Nutt, Monica Gagliano, Wade Davis, and many more, this publication will serve as a vital resource for researchers, practitioners, and anyone curious about the profound role psychoactive plants play in human health, consciousness, and culture. 

Stay tuned for the release of ESPD55, a co-creation between Synergetic Press and the McKenna Academy for Natural Philosophy

 

Stay in the Loop — Please leave us your contact details, we will send you information about the release of ESPD55 this Summer. 

4 + 15 =

Speakers and Participants in the Ethnopharmacologic Search for Psychoactive Drugs Conference, hosted by the Mckenna Academy, May 2022

Future Water Association Awards “The Language of Water”

Future Water Association Awards “The Language of Water”

The Future Water Association Honors The Language of Water with Future Water Award

In a powerful acknowledgment of work that bridges science, storytelling, and community-based restoration, the Future Water Association has awarded its prestigious Future Water Award to Minni Jain and Philip Franses for their groundbreaking work presented in The Language of Water.

Held annually, the Future Water Awards celebrate innovation, creativity, and vision in the water sector—recognizing those who are reshaping how we understand and engage with the world’s most precious resource. This year, The Language of Water stood out as an exemplary publication that transcends traditional boundaries of the water industry by weaving together cultural narratives, indigenous wisdom, and tangible community-led solutions for water restoration.

     “Water has its own language, a rhythm and intelligence that flows through all life. This book teaches us to listen.”                     — Future Water Association, 2025

Published by Synergetic Press, The Language of Water is more than a book—it is a movement. Authored by Minni Jain, Director of The Flow Partnership, and Philip Franses, systems thinker and teacher, the work draws from real-life stories across India, Africa, Europe, and beyond. It shares how communities are reviving traditional water-harvesting techniques to bring life back to rivers, soils, and people—healing not only ecosystems, but also the social and spiritual fabric of their environments.

In awarding the book, the Future Water Association commended Jain and Franses for their “courageous and creative approach to communication and cultural storytelling,” underscoring the importance of narrative and education in driving meaningful change in the water sector.

Based in the UK, the Future Water Association is a modern, innovative, not-for-profit organization that represents professionals and suppliers across the water and wastewater industry. For over 30 years, it has acted as the voice of the sector—engaging with government, regulators, and utility providers to influence policy, promote education, and drive innovation. Its annual awards align with World Water Day and aim to shine a light on transformative projects shaping the future of water management.

This year’s award adds another accolade to The Language of Water’s growing recognition as a vital contribution to the global water dialogue. Its pages are filled with deeply moving reflections and hopeful solutions—reminding us that water is not only a technical issue, but also a cultural, emotional, and spiritual one.

“We are honored to receive the Future Water Award. This book is the voice of the waters that still flow inside us all—waiting to be heard, waiting to be healed.”
— Minni Jain & Philip Franses

As the global water crisis intensifies, The Language of Water offers a compelling path forward—inviting readers from all walks of life to reconnect with the element that unites us all. The recognition by the Future Water Association confirms what many already feel: this book is a timely and vital offering, inspiring a new generation of water stewards across the world.

The Language of Water is available from your favorite bookstore or directly from the publisher, Synergetic Press. 

Psychedelics Uncensored With Benjamin Cassiday

Psychedelics Uncensored With Benjamin Cassiday

Why printed knowledge matters more than ever, and which banned-worthy
books to read now

Synergetic Press is proud to announce an affiliate partnership with Psychedelics.com, a platform at the forefront of psychedelic education and media. Dedicated to bridging soul and science, Psychedelics.com offers ethically grounded, expert-driven content to support those exploring the healing and transformative potential of psychedelics. In a time when censorship and erasure threaten access to meaningful information, Psychedelics.com remains a strong advocate for free speech and the preservation of psychedelic wisdom. Together, we’re working to ensure that visionary knowledge remains accessible, uncensored, and alive for generations to come.

Below, is an inspired piece by Psychedelics.com’s Operations Manager, Benjamin Cassiday, about the role Synergetic Press has played and the future of free press media.

Knowledge is power.
And those in power know it.

That’s why, in this moment—when books are being banned and burned, when government websites are being scrubbed, and when almost everything we read is digital, editable, and erasable—we need to protect what matters most.

Because if we don’t own the books, we risk losing the truths inside them.

This is a core pillar of Psychedelics Uncensored:

We can’t let the knowledge that transformed lives, expanded minds, and healed generations be rewritten—or deleted.

And few have done more to preserve our radical library of awakening than Synergetic Press.

Since 1984, Synergetic has been broadcasting ideas deemed too disruptive, too spiritual, or contrary to the status quo for the mainstream. Books that whisper secrets of the earth, shout truths about consciousness, and offer blueprints for a new planetary culture.

These aren’t just words on paper—they’re sparks from the last psychedelic revolution, reignited just in time to light the fire of the one happening now.

Whispers From the Last Revolution

Synergetic Press has built a sacred library for the psychedelic revolution—one book at a time.

They’ve published the raw, uncensored voices of visionary leaders at times when no one else was willing to work with them.

Some of our favorite “dangerous authors” include:

  • 📘 Albert Hofmann — The father of LSD reminds us that molecules can be spiritual teachers.

  • 📕 Ram Dass — From Harvard to India to eternity, Synergetic helps keep the “Be Here Now” ethos alive.

  • 🎨 Alex Grey — Psychedelic mysticism made visual—Grey’s art opens the third eye wide.

  • 💞 Ann Shulgin — Emotional healing, heart-opening compounds, and the legacy of love through chemistry.

  • 🌿 Beatriz Caiuby Labate — Decolonizing psychedelics through Indigenous wisdom and academic fire.

  • 🌌 Dennis McKenna — From ayahuasca to alien intelligence, Dennis brings science and story to the frontier.

  • 🧠 Stanislav Grof — A pioneer of LSD psychotherapy and transpersonal psychology.

  • 🕵️ William Leonard Pickard — Imprisoned alchemist, philosopher, and author of one of the most daring psychedelic memoirs ever written.

Support Small, Save Big, Share Wisdom

Why buy from Synergetic Press?

  • Support independent publishing that champions transformative ideas.

  • Save 20% on your purchase using .

  • Gift a loved one the wisdom that can spark personal and societal change.

 

The Voice Of Synergetic Press

Deborah Parrish Snyder is the co-owner and CEO of Synergetic Press, which has published over 40 books on ethnobotany, psychedelics, biospherics, and social and ecological justice.

👉 Watch her conversation here with Joe More of Psychedelics Today

Synergetic Is More Than a Publisher

Founded by Deborah Parrish Snyder, Synergetic Press is rooted in activism, experimentation, and Earth stewardship. It’s home to a constellation of radical projects, including:

  • 🧬 Biosphere 2 — The legendary closed ecological system experiment that became a symbol of planetary research.

  • 🌱 Synergia Ranch — A regenerative farm, retreat center, and the beating heart of Synergetic’s operations in New Mexico.

  • 🌀 The Institute of Ecotechnics — A global project exploring the intersection of ecology, innovation, and consciousness.

  • 🎭 The Theater of All Possibilities — A 1967-born art movement that blended performance with radical thought.

 

A Journey Through Interoception

I’ve just finished reading How to Change Your Body: The Science of Interoception and Healing Through Connection to Yourself and Others, a book that’s completely changed the way I relate to the physical sensations of my body, especially during psychedelic experiences and healing from trauma.

Next week, I’ll share a summary and some lessons I’ve learned and applied

    Final Word

    When they say books can change the world—this is what they mean.

    Support the ones who’ve been pushing boundaries for 40 years.

    Read the books you’ve been warned about.

    💬 What’s One Book That Changed Your Mind Forever?
    Hit reply and tell us. We’re building a living archive of mind-shaping titles.

    📍 Come see visit our book Psychedelics.com at Psychedelic Science 2025 for a chance to win $500 worth of Synergetic Press Books. Use code PSY15 for 15% off your ticket!

    Expand Your Mind, Expand Your Toolkit

    Understanding this movement means knowing the voices, media, and conversations shaping it. Whether you’re just starting out or deep in the work, these handpicked resources help you stay sharp, curious, and connected:

    • 🌟 The Most Influential People in Psychedelics – From underground icons to clinical pioneers, this list captures the individuals driving the psychedelic renaissance forward. Read the article »

    • 🎬 Psychedelic Movies That Break the Mold – Cinema has long been a mirror for altered states. This guide curates films that capture the spirit, mystery, and edge of psychedelia. Explore the list »

    • 🎧 Podcasts That Go Deeper – From science and spirituality to culture and consciousness, these podcasts aren’t background noise — they’re gateways. Perfect for your next walk or trip prep. Find your next favorite episode »


    ✅ No one can stop you from seeing what’s delivered directly to your email.
    You’re already subscribed—congratulations!

    You beat the algorithm 😉

    Thank you for joining us as we continue to navigate this ever-changing landscape.


    P.S. Explore what they don’t want you to see—check us out on X (Twitter) and Instagram, and dive deeper into all things psychedelic on our website. 🌐✨

    A Magical Evening of Grandmothers’ Wisdom in Santa Fe

    A Magical Evening of Grandmothers’ Wisdom in Santa Fe

    Celebrating generational wisdom with Grandmother Flordemayo and Heather at Collected Works in Santa Fe.

    Thank you for joining us!

    This past April 6th, a heartwarming and unforgettable gathering took place at the Collected Works Bookstore & Coffeehouse in Santa Fe, New Mexico. Co-hosted by Synergetic Press, the event brought together a vibrant community of wisdom seekers for a rare and beautiful evening in the presence of Grandmother Flordemayo and her daughter, Heather. Together, they shared stories, insights, and deep reflections that touched everyone in attendance.

    The space was filled with reverence and joy as Grandmother Flordemayo offered a live reading from her chapter in Grandmothers’ Wisdom, bringing her words to life with the power of her voice and spirit. Attendees had the privilege of hearing about her personal journey—from her roots in Central America to her sacred work in New Mexico—and the founding of The Path, a nonprofit dedicated to preserving Indigenous wisdom, spiritual teachings, and heirloom seeds for future generations.

    One of the most touching moments of the afternoon was the sacred conversation between Flordemayo and Heather. Their dialogue, infused with generational wisdom and shared purpose, illuminated the powerful legacy they are building together. It was a moving reminder of the importance of protecting Indigenous traditions and uplifting the next generation of wisdom keepers.

    The event concluded with a heartfelt Q&A and community dialogue, where attendees expressed their deep gratitude, asked thoughtful questions, and connected with one another through shared reverence for Indigenous knowledge and Earth-based spirituality. Signed copies of Grandmothers’ Wisdom were made available after the event, offering a cherished memory of the day to take home.

    We are so grateful to everyone who joined us, and to Grandmother Flordemayo and Heather for their generosity of spirit. It was an honor for Synergetic Press to co-present this event and hold space for such a sacred gathering.

    Thank you for being part of this celebration of love, resilience, and ancestral wisdom. May the teachings of the grandmothers continue to guide us forward.

    The Roots and Future of the Psychedelic Movement

    The Roots and Future of the Psychedelic Movement

     

    A Reflection on Our Unfolding Psychedelic Revolution

     

    There are moments in history when a current beneath the surface begins to surge. It pulls at our dreams, whispers through art, and howls in the language of the soul. We’re living through one of those moments now.

    Some call it a renaissance. Others, a revolution.
    But what’s truly happening in the psychedelic movement goes deeper than science, policy reform, or the resurgence of plant medicine.

    This is a regeneration of consciousness—an evolutionary pulse echoing through our bones, shaking the cages of conformity, and urging us toward something wholly unfamiliar yet deeply remembered.

    We’ve been here before.

     

     

    The Ancients Knew

    Long before Western minds claimed discovery, our ancestors danced with the stars on mountain tops and listened to the mycelium beneath their feet. In the caves of Tassili n’Ajjer, 10,000-year-old paintings depict beings crowned with mushrooms—perhaps humanity’s earliest documentation of sacred communion.

    The Mazatec in Mexico, the Shipibo in the Amazon, and Native American tribes across Turtle Island have long known what we are just remembering: psychedelics are not drugs.
    They are portals. They are kin. They are teachers.

    Entheogens were never about escapism. They were doorways into the deeper architecture of existence—used in ceremony, in healing, and in communion with the Earth.
    What we are calling a renaissance is merely a return.

     

     

    The Alchemy of Discovery

    In 1938, Swiss chemist Albert Hofmann synthesized LSD, only to discover its mind-bending effects five years later when he took a now-mythic bicycle ride through the streets of Basel.

    Few know that Hofmann believed LSD wasn’t just a compound—but a “medicine for the soul.”

    Meanwhile in 1897, Arthur Heffter had isolated mescaline from the peyote cactus—blazing a trail of chemical curiosity that would lead to profound questions of perception, self, and spirit.

    When R. Gordon Wasson sat with María Sabina, the Mazatec curandera, in 1955, the Western world was introduced to psilocybin mushrooms. But what’s often left out is how that encounter disrupted her life. Sacred knowledge, once protected, was suddenly extracted.

    This renaissance must remember its roots. Or it will repeat the violence of erasure.

     

     

     

    The Sixties Broke the Mold (and Our Illusions)

    By the 1960s, LSD was not just being studied—it was shaping the culture.
    Timothy Leary’s call to “Turn on, tune in, drop out” wasn’t just about dropping acid—it was about stepping off the treadmill of capitalist hypnosis.

    Music transformed into prayer. Protest became poetry.
    Woodstock wasn’t just a music festival. It was a ritual of remembrance.

    But the system bit back.
    In 1971, Nixon declared war—not just on substances, but on consciousness itself. Research halted. Doors shut. Visionaries silenced.

    But as always, the underground held the flame.

     

     

    Carriers of the Flame

    Indigenous communities never stopped.
    Peyote ceremonies carried on in secret. Ayahuasca began to whisper its way westward through Santo Daime and UDV churches.

    And in 1986, Rick Doblin planted a seed by founding MAPS. A new era had begun—one that would blend science with soul, research with ritual.

    Raves became spiritual pilgrimages. Ecstasy gave birth to communal heart-openings.
    The “underground” wasn’t underground. It was the mycelial web of our collective becoming.

    The Renaissance: Not Just a Reawakening, But a Reworlding
    Today, we are living with the veil lowered.

    We see emotions. We sense intentions. We feel the Earth thinking through us.
    And in this vulnerable, psychically porous state, we are being asked:

    What do you do with this awareness?
    What world will you build from this place of soul-sight?

    This renaissance is not about glorifying trips or romanticizing ancient rituals.
    It’s about what we do with what we see.

    It’s about healing the traumas encoded in our systems.
    It’s about decolonizing our practices and honoring the medicines with reciprocity.
    It’s about using altered states not to escape—but to reimagine society itself.

    We are being invited into a third option—one that isn’t bound by the binary of tradition or rebellion. A new way entirely. One seeded in soul, watered by spirit, and grown in collective soil.

     

     

    Guardians of the Vision: The Bibles of Psychedelic Culture

    At Synergetic Press, we are honored to house the works of the very visionaries who shaped this movement.

    Sasha and Ann Shulgin’s PIHKAL and TIHKAL—chemical love letters to the inner cosmos.

    Dennis McKenna, who carries the psychedelic flame with botanical brilliance.

    Leonard Pickard, whose mythic narrative The Rose of Paracelsus redefines what literature can be.

    Albert Hofmann’s LSD: My Problem Child—a scientific memoir soaked in soul.

    And so many more voices—keepers of gnosis, scribes of the ineffable.

    These aren’t just books. They’re maps.
    They are bibles for the seekers, the scientists, the artists, and the ancestors-in-the-making.

     

     

     

     
    What Now?

    Psychedelic capitalism is rising. Ethics are being tested.
    We must remain vigilant: this revolution is not for sale.

    Let’s build cultures of reciprocity, not extraction.
    Let’s form rituals rooted in reverence, not trend.
    Let’s remember that awakening isn’t the end—it’s the beginning of a deeper responsibility.

    We are here to regenerate the world, not just our minds.
    The psychedelic renaissance is not a return to the past, nor a projection of the future.
    It is a portal through which we remember we are creators, now.

    Let’s walk through that portal together.

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