Ann Shulgin (1931–2022) co-founded Transform Press in 1991 with her husband, Alexander "Sasha" Shulgin, out of their shared passion and commitment to an uncensored examination of psychoactive compounds. Together they co-authored PiHKAL: A Chemical Love Story (1991) and TiHKAL: The Continuation (1997), and led discussion groups on psychedelics and psychopharmacology for many years. Ann also played an integral role in The Nature of Drugs, helping record Sasha's landmark lecture series and contributing to the editing of all three volumes — a testament to their enduring collaborative legacy.

They contributed jointly to several other publications including The Secret Chief, The Secret Chief Revealed, Entheogens and the Future of Religion, and Ecstasy: The Complete Guide.
Ann served as a lay therapist facilitating the use of MDMA and 2C-B in therapeutic settings while those substances were legal. She brought a Jungian orientation to her work, placing particular emphasis on Shadow integration and the theme of spirituality and unification with the divine in all things.